Generally speaking, if you get into a car accident, you are safer if you are in a pickup truck than if you are in a car. Many people who don't need trucks for work or any other purpose just pick them because of this relative safety.
So, what makes a pickup truck safer? There are numerous factors. Height is important. If you're in a low passenger car, an accident may push the front of the other vehicle into your window or passenger compartment, but the same wreck in a pickup truck could send the other car below your feet. You can still get injured, but the odds of death are lower.